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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Homocysteine
drug:
Raloxifene
Research Papers that Mention the Interaction
“After 24 months, plasma homocysteine levels were decreased significantly in the raloxifene 150-mg and CEE groups compared with both baseline (-13% and -10%, respectively) and placebo values (-15% and -11%, respectively).”
Randomized, double-blind, placebo-controlled study of the effects of raloxifene and conjugated equine estrogen on plasma homocysteine levels in healthy postmenopausal women.“For example, raloxifene lowers serum levels of cholesterol and homocysteine , attenuates oxidation of low‐density lipoprotein, inhibits endothelial–leucocyte interaction, improves endothelial function and reduces vascular smooth muscle tone.”
“Although glucose metabolism was unaffected, homocysteine , a bone quality marker, was significantly decreased at 6 months in the raloxifene group.”
“The use of raloxifene , the most studied selective estrogen receptor modulator, is associated with a modest reduction in homocysteine.”
“Recently, two randomized controlled trials demonstrated that raloxifene lowers plasma Hcy levels in postmenopausal women, similar to the reduction obtained with HRT.”
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