Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Homocysteine and Raloxifene

supplement:

Homocysteine

Research Papers that Mention the Interaction

After 24 months, plasma homocysteine levels were decreased significantly in the raloxifene 150-mg and CEE groups compared with both baseline (-13% and -10%, respectively) and placebo values (-15% and -11%, respectively).
Fertility and sterility  •  1998  |  View Paper
For example, raloxifene lowers serum levels of cholesterol and homocysteine , attenuates oxidation of low‐density lipoprotein, inhibits endothelial–leucocyte interaction, improves endothelial function and reduces vascular smooth muscle tone.
Clinical and experimental pharmacology & physiology  •  2007  |  View Paper
Although glucose metabolism was unaffected, homocysteine , a bone quality marker, was significantly decreased at 6 months in the raloxifene group.
Journal of Bone and Mineral Metabolism  •  2012  |  View Paper
The use of raloxifene , the most studied selective estrogen receptor modulator, is associated with a modest reduction in homocysteine.
Climacteric : the journal of the International Menopause Society  •  2006  |  View Paper
Recently, two randomized controlled trials demonstrated that raloxifene lowers plasma Hcy levels in postmenopausal women, similar to the reduction obtained with HRT.
Clinical chemistry and laboratory medicine  •  2001  |  View Paper