“Furthermore, the increased NADPH oxidase activity induced by L‐homocysteine was significantly reversed by probucol in THP‐1 cells.”
“ Probucol dose‐dependently suppressed the differentiation and reactive oxygen species productions of inflammatory monocytes induced by L‐homocysteine.”
“ Probucol prevented L‐homocysteine‐induced inflammatory monocytes differentiation and its reactive oxygen species generation probably through inhibiting NADPH oxidase activity.”