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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Homocysteine
Research Papers that Mention the Interaction
“Removal of endothelium (P < 0.05), pretreatment with a nitric oxide (NO) synthesis inhibitor l-N(G)-monomethylarginine , 200 microM, P < 0.001), or pretreatment with a hydroxyl radical ((*)OH) scavenger (mannitol, 10 mM, P < 0.001) significantly attenuated contraction potentiated by Hcy plus Fe(2+).”
Protective effect of melatonin against homocysteine-induced vasoconstriction of human umbilical artery.“This effect of homocysteine was significantly inhibited in the presence of NG-monomethyl-L-arginine or actinomycin D. The homocysteine-induced nitrite production was accompanied by increased inducible NO synthase mRNA and protein accumulation.”
Homocysteine increases nitric oxide synthesis in cytokine-stimulated vascular smooth muscle cells.
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