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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Homocysteine
supplement:
Multivitamin Preparation
Research Papers that Mention the Interaction
“Additional administration of vitamin supplements induced a further decrease in tHcy and an increase in folate.”
“After multivitamin supplementation, we observed a trend toward further decrease in tHcy concentrations and a significant increase in serum folate and cobalamin concentrations.”
Effects of folic acid fortification and multivitamin therapy on homocysteine and vitamin B(12) status in cardiac transplant recipients.“Treatment with a daily multivitamin containing 1 mg folate significantly lowered tHcy levels in all patients by 19.2%.”
“However, tHcy was not normalized in the majority of patients receiving preparation A. CONCLUSION The reduction of tHcy achieved by a multivitamin containing 800 microg folic acid was substantial and even higher than the reduction reported in supplementation studies using higher doses of folic acid alone.”
“Consequently, our differential display analysis revealed that homocysteine alters the expressivity of multiple proteins , especially ER stress-responsive ones.”
“ Vitamin B supplements can lower the serum homocysteine ( Hcy) level, but whether it can prevent cognitive decline or not remains unclear.”
“The … to homocysteine ratio was higher in individuals who consumed vitamin supplements (median, 1.9; interquartile range [IQR], 1.5-2.6) compared with those who did not (median, 1.8; IQR, 1.3-2.3; P < .001) and increased per each quartile increase of vitamin B12 or folate.”
“The role of hyperhomocysteinemia (HHcy) as a cardiovascular risk factor remains a matter of debate, while it correlates with folates, it demonstrates inverse correlation with plasma homocysteine (Hcy) levels and vitamin B12 levels and reduces plasma Hcy levels following supplementation with multivitamins.”
“The co-ingestion of MVit + N3 provides synergistic affects on HCY , hsCRP, and plasma TG.”
“… multivitamin … homocysteine but did not reduce the rates of the primary outcome (n=547 total events; hazards ratio [95 confidence interval]=0.99 [0.84 to … 1.26]), or dialysis-dependent kidney failure (n=343 events; 1.15 [0.93 to 1.43]) compared to the low-dose multivitamin.”
“ Multivitamin supplementation decreased levels of homocysteine and increased levels of vitamin B6 and B12, with a trend for vitamin E to increase.”
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