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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Homocysteine
supplement:
Glycocyamine
Research Papers that Mention the Interaction
“Serum B vitamins were not affected by either placebo or GAA intervention (P > 0.05).ConclusionResults indicate that low-to-high dosages of exogenous GAA can increase serum concentrations of Cr and T-Hcy while not depleting the B vitamins pool available for remethylation of homocysteine.”
Dose–response effects of oral guanidinoacetic acid on serum creatine, homocysteine and B vitamins levels“In particular, an increase in serum homocysteine after GAA administration can be regarded as critical and should be prevented.”
“ GAA supplementation markedly increased the plasma homocysteine concentration in rats fed with the 10C diet, whereas it did not increase the plasma homocysteine concentration in rats fed with the 40C diet.”
High-Casein Diet Suppresses Guanidinoacetic Acid-Induced Hyperhomocysteinemia and Potentiates the Hypohomocysteinemic Effect of Serine in Rats“ GAA supplementation dose-dependently decreased the hepatic S-adenosylmethionine (SAM) concentration and the activity of cystathionine beta-synthase (CBS) and increased the hepatic S-adenosylhomocysteine (SAH) and homocysteine concentrations.”
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