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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Homocysteine
supplement:
Epigallocatechin Gallate
Research Papers that Mention the Interaction
“treatment with high doses (100–2000 mg/kg) of EGCG significantly decreased the intestinal levels of SAM and SAH, decreased the plasma levels of methionine, and elevated the plasma levels of homocysteine.”
Reversal of hypermethylation and reactivation of genes by dietary polyphenolic compounds.“ EGCG can inhibit AT-1R and affect ERK1/2 and p38MAPK signaling pathways, resulting in the decrease of VSMC proliferation induced by Hcy.”
“Pretreatment with epigallocatechin-3-gallate or 5-Aza inhibited such effects of homocysteine.”
“We found that supplementation of EGCG could rescue deficit of spatial memory induced by homocysteine.”
Epigallocatechin-3-Gallate Protects against Homocysteine-Induced Brain Damage in Rats.“Results: The pretreatment of irradiated rats with EGCG significantly ameliorated the increased plasma levels of homocysteine , amyloid β, TNF-α and IL-6 levels and the decrease of dopamine and serotonin.”
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