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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Homocysteine and 4-Phenylbutyric Acid

Research Papers that Mention the Interaction

In vitro, as compared to calcifying medium alone, Hcy treatment further increased alkaline phosphatase activity, calcium content, and calcium nodule number in human aorta vascular smooth muscle cells (HA-VSMCs), all blocked by IMD or PBA pretreatment.
Journal of cardiovascular pharmacology and therapeutics  •  2019  |  View Paper
Hcy also enhanced endoplasmic reticulum (ER) stress in T cells, and inhibition of ER stress with 4-phenylbutyric acid blocked Hcy-induced T-cell activation.
Protein & Cell  •  2016  |  View Paper