Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Histidine and Steroids

supplement:

Histidine

Research Papers that Mention the Interaction

The present data are in line with previous observations of the … histidine on the growth of experimental animal tumours, add evidence that histidine concentration influences the control … cell proliferation by sex steroids , and suggest a possible use of histidine in association … progestational drugs in the treatment of human neoplasia.
Pharmacological research  •  1997  |  View Paper
Added progestins, but also steroids without affinity for uteroglobin, prevent only partially the modification of histidine , suggesting that this amino acid is not located at the steroid binding site.
Therefore, although histidine is not directly involved in the interaction with steroid it seems to be crucial for stabilizing an “active” conformation of the protein.
Journal of steroid biochemistry  •  1980  |  View Paper