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Last Updated: 5 months ago

Possible Interaction: Histidine and Pyrilamine

supplement:

Histidine

Research Papers that Mention the Interaction

This effect of l-histidine on behavior was completely abolished by simultaneous administration of pyrilamine or ketotifen (brain-penetrating histamine H(1) receptor antagonists; 10mg/kg each, i.p.),
Pharmacology Biochemistry and Behavior  •  2010  |  View Paper
The histamine H(1) receptor antagonist pyrilamine (1 microg/site) abolished the ameliorative effects of histidine on working memory deficits, whereas both pyrilamine and the H(2) receptor antagonist cimetidine (0.5 microg/site) abolished the effect of histidine on reference memory.
Clinical and experimental pharmacology & physiology  •  2009  |  View Paper
The reduction in the late VEP components induced by pyrilamine and diphenhydramine was significantly antagonised by pre-treatment of histidine (200 and 500 mg/kg), but not by physostigmine even at a dose of 0.01 mg/kg.
Brain Research Bulletin  •  2003  |  View Paper
The ameliorating effect of histidine was antagonized by pyrilamine (2-5 mg/kg), a H1-antagonist, but not by zolantidine, a H2-antagonist.
The ameliorating effect of histidine was antagonized by pyrilamine (2-5 mg/kg), a H1-antagonist, but not by zolantidine, a H2-antagonist.
Acta pharmacologica Sinica  •  2002  |  View Paper
Intraperitoneal injection of histidine inhibited the EEG seizures induced by pyrilamine , diphenhydramine or chlorpheniramine; however no antagonism was observed with physostigmine.
Brain Research  •  2000  |  View Paper
The effect of pyrilamine was more potently antagonized by histidine and less potently antagonized by physostigmine as compared to diphenhydramine, promethazine and cyproheptadine.
Methods and findings in experimental and clinical pharmacology  •  2000  |  View Paper
The increase in rCBF in the hippocampus induced by L-histidine was antagonized by both H1 and H2 antagonists (diphenhydramine, pyrilamine and zolantidine).
Methods and findings in experimental and clinical pharmacology  •  1999  |  View Paper
Moreover, the ameliorating effect of histidine was antagonized by a histamine H1-receptor antagonist, pyrilamine , but not by zolantidine, a histamine H2-receptor antagonist.
Methods and findings in experimental and clinical pharmacology  •  1995  |  View Paper
Moreover, the ameliorating effect of histidine was antagonized by a histamine H1 receptor antagonist, pyrilamine.
Life sciences  •  1995  |  View Paper
The effects of histidine , as well as histamine, were blocked by mepyramine , a histamine H1-receptor antagonist, and by ranitidine, an H2-antagonist.
Proceedings of the Royal Society of London. Series B: Biological Sciences  •  1991  |  View Paper