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“The crystal structure of the E. coli enzyme suggests that this proline is important in positioning the active site histidine (His-166) near the substrate.”
The Journal of Biological Chemistry • 1996 | View Paper
“Our purpose in the present study was to investigate the influence of proline on the suppressive effect of histidine on food intake and accumulation of body fat.”
“Our results indicate that proline inhibits the influence of histidine on food intake and accumulation of body fat.”
“We recently suggested that proline might decrease the suppressive effect of histidine on food intake.”
“The beneficial effect of proline was prevented by the addition of excess betaine, glycine, and histidine , indicating competitive inhibition of transport-mediated uptake.”
Korean journal for food science of animal resources • 2018 | View Paper
“The detector response was found to be analyte-dependent, e.g. tryptophan gives no response, and the response for histidine is about 13-fold lower than that of proline.”
“The presence of D or L histidine in TRF has a profound influence on the 13C chemical shifts of proline , whereas those of pyroglutamate are unaffected.”