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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Histidine
drug:
Methamphetamine
Research Papers that Mention the Interaction
“These data suggest that l-histidine modifies the effects of METH through central histamine H(1) receptors.”
Pretreatment with l-histidine produces a shift from methamphetamine-induced stereotypical biting to persistent locomotion in mice“ L-histidine (400 mg/kg), a precursor of histamine, significantly enhanced the discriminative stimulus effects of cocaine and methamphetamine.”
“Chronic treatment with L-histidine (750 mg/kg) plus METH inhibited the METH-induced argumentation of stereotyped behavior, while that with FMH (100 mg/kg), pyrilamine (5 mg/kg) or zolantidine (5 mg/kg) potentiated it.”
“Pretreatment with a … of HA, L-histidine (750 mg/kg), … inhibited the METH (3 mg/kg)-induced stereotyped behavior, whereas pretreatment with an inhibitor of HA synthesis, α-fluoromethylhistidine (FMH) (100 …/kg), an H1 antagonist pyrilamine (5 mg/kg) or an H2 antagonist zolantidine (5 mg/kg) enhanced it.”
“ HIS (1000 mg/kg) completely inhibited the hypermotility induced by MAMP (1 mg/kg).”
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