Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Histidine and Mannitol

supplement:

Histidine

Research Papers that Mention the Interaction

Furthermore, when L‐histidine, a scavenger of singlet oxygen and hydroxyl radical, or D‐mannitol , a scavenger of hydroxyl radical, was used concurrently, the survival rate of tumor cells was significantly higher with L‐histidine.
Japanese journal of cancer research : Gann  •  1999  |  View Paper
Depletion of histidine is partially prevented by bathophenanthrolinedisulfonate and mannitol , while lysine and arginine depletions remain unaffected.
Chemical research in toxicology  •  1992  |  View Paper
Furthermore, when D‐mannitol was used with SPFX, the survival rate of tumor cells after irradiation was comparable with that when SPFX alone was applied, but when L‐histidine was used concurrently, the survival rate of tumor cells was significantly higher than that when SPFX alone was applied.
Cancer science  •  2004  |  View Paper
Superoxide dismutase and mannitol did not decrease the killing effect whereas mannitol completely prevented the formation of micronuclei and of SCEs induced by H2O2 or by H2O2 plus L-histidine.
Mutation research  •  1990  |  View Paper