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Discover Supplement-Drug Interactions

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Last Updated: 5 years ago

Possible Interaction: Histidine and Insulin

supplement:

Histidine

drug:

Insulin

Research Papers that Mention the Interaction

“Consistently, the transport of the substrate l-histidine was increased with short, but not long, treatment by insulin in both H2.35- and SNAT3-transfected COS-7 cells.”
Journal of Biological Chemistry  •  2005  |  View Paper
“ Histidine or carnosine treatments significantly improved insulin sensitivity and attenuated hyper-insulinemia (P<0.05).”
European journal of pharmacology  •  2011  |  View Paper
“For the leg, the uptake of His and Thr were decreased by insulin , whereas the infusion of AA stimulated the uptake of total essential AA.”
Journal of dairy science  •  2001  |  View Paper
“ Histidine (10 and 25 mg/kg) caused a small but significant reduction in the plasma insulin level.”
General and comparative endocrinology  •  1977  |  View Paper
“Previous studies have demonstrated that the potency and thermodynamic stability of human insulin are enhanced in concert by substitution of ThrA8 by arginine or histidine.”
The Journal of Biological Chemistry  •  2001  |  View Paper