Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Histidine and Glutamic Acid

supplement:

Histidine

supplement:

Glutamic Acid

Research Papers that Mention the Interaction

Molecular modeling analysis reveals that the glutamic acid , which is negatively charged, interacts with positively charged histidine located at position 55, thereby stabilizing KIR2DL2/L3 dimer and reducing entropy loss when KIR2DL2/3 binds to HLA-C ligand.
Scientific reports  •  2016  |  View Paper
The hemoglobin instability was attributed to an abnormal interaction between the substituted glutamic acid and histidine at position β 77 .
Blood  •  1970  |  View Paper
Glutamic acid provoked considerable discomfort to the subjects and histidine caused some nausea.
Acta anaesthesiologica Scandinavica  •  1970  |  View Paper
The system N substrate, L-glutamic acid gamma-monohydroxamate, also inhibited uptake of L-histidine.
American journal of physiology. Lung cellular and molecular physiology  •  2002  |  View Paper
Histidine also increased glutamic acid uptake in astrocytoma cells, but reduced it in neuroblastoma cells.
Neurochemical Research  •  2004  |  View Paper