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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Histamine
supplement:
Vitamin B 6
Research Papers that Mention the Interaction
“The possible mechanism of the inhibitory action of PLP and complex with histamine and other amines on rat intestinal histaminase activity are discussed.”
Phosphopyridoxal complexes with histamine and histidine (3) the influence of presumed complex on activity of rat intestinal histaminase“Exogenous histamine prevented the reactivation of HD activity by pyridoxal 5-phosphate in deficient rats but was without effect in vitro .”
“Meanwhile, recent studies have revealed that vitamin B6 treatment increases cardiac levels of imidazole dipeptides (e.g., carnosine, anserine, and homocarnosine), histamine , and γ-aminobutyric acid (GABA) and suppresses P2X7 receptor-mediated NLRP3 inflammasome.”
Emerging cardioprotective mechanisms of vitamin B6: a narrative review“Since PLP is able to form a cyclic product with histidine and histamine, the possibility of complex formation between PLP and histamine formed during a decarboxylation reaction was examined too.”
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