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“ Histamine mimicked the depolarizing effect of ovalbumin in a concentration-dependent manner (0.1-10 microM) and caused a transient increase and decrease in membrane resistance.”
The American journal of physiology • 1995 | View Paper
“Parallel to mast cell activation, the levels of histamine in serum and supernatant of rat peritoneal lavage solution were remarkably increased after OVA treatment.”
“The course of treatment with antibodies to histamine suppressed production of allergen-specific IgE and IgG1 in mice 2-fold immunized with ovalbumin in doses of 100 and 0.5 mg, respectively.”
British journal of pharmacology • 1999 | View Paper
“In hearts from rats that were previously sensitized by an injection of an ovalbumin-alumina adsorbate, ovalbumin induced a marked increase of histamine and serotonin efflux.”
Methods and findings in experimental and clinical pharmacology • 1994 | View Paper
“In guinea pigs treated with anti-IL-5, the development of hyperreactivity to histamine and arecoline after ovalbumin challenge is completely inhibited.”
Journal of the autonomic nervous system • 1990 | View Paper
“These results indicate that ovalbumin sensitization significantly affects the tracheal response to Ach, His and PAF, an effect that appears to be mediated by arachidonic acid metabolites.”
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas • 1989 | View Paper
“ Ovalbumin induced the release of 7.9 ng of histamine , 40 pg of immunoreactive sulfidopeptide-leukotriene, and 140 pg of immunoreactive-PgD2 per ganglion.”