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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Histamine
supplement:
Oligosaccharides
Research Papers that Mention the Interaction
“It is proposed that oligosaccharides produced by heparinase I-catalyzed depolymerization can inhibit the enzyme by binding to the imidazolium group of histidine-203, … cysteine-135 forms the catalytic domain of heparinase I. The increased rate and extent of depolymerization are attributed to competitive binding of the oligosaccharides … histamine.”
Hexasaccharides from the histamine-modified depolymerization of porcine intestinal mucosal heparin.“It was found that Tri-GalA and POS could attenuate the release of β-hexosaminidase and histamine , reduce the production of IL-4 and inhibit the extracellular Ca2+ influx of RBL-2H3 cells.”
The inhibition of pectin oligosaccharides on degranulation of RBL-2H3 cells from apple pectin with high hydrostatic pressure assisted enzyme treatment.
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