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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Histamine
supplement:
Magnesium Cation
Research Papers that Mention the Interaction
“Calcium and sodium ions have little effect on histamine binding whereas magnesium ions decrease the affinity of histamine for the radioantagonist binding sites about tenfold.”
Regulation of membrane histamine H1-Receptor binding sites by guanine nucleotides, mono- and divalent cations“In a normal solution, Mg++ increased the EC50 value for histamine , but did not alter the EC50 value for norepinephrine or the maximum force induced by norepinephrine or histamine.”
“The results indicate that in the pulmonary artery, Mg++ alters the sensitivity to histamine but not to norepinephrine, and may differentially inhibit bound Ca++ release by norepinephrine and histamine.”
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