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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Histamine
supplement:
Kaempferol
Research Papers that Mention the Interaction
“ARE, quercetin, and kaempferol inhibited secretion of β-hexosaminidase and histamine , and reduced the production and mRNA expression of interleukin-4 and tumor necrosis factor-α.”
Aceriphyllum rossii extract and its active compounds, quercetin and kaempferol inhibit IgE-mediated mast cell activation and passive cutaneous anaphylaxis.“ Kaempferol significantly decreased the release of histamine , IL-6, IL-8, IL-1β and TNF-α of activated HMC-1 mast cells (P<0.01).”
“Its main constituents, chlorogenic acid and luteolin potently inhibited PCA reaction induced by IgE-antigen complex as well as pruritus induced by compound 48/80 or histamine.”
Anti-allergic effects of fermented Ixeris sonchifolia and its constituent in mice.“The nifedipine (10 microM)-remaining tension of histamine (30 microM)-induced precontractions was further relaxed by luteolin , suggesting that no matter whether VDCCs were blocked or not, luteolin may have other mechanisms of relaxant action.”
“The vascular permeability increase induced by passive cutaneous anaphylaxis or histamine injection was also significantly reduced by luteolin.”
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