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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Histamine
supplement:
Epigallocatechin Gallate
Research Papers that Mention the Interaction
“… EGCG , the number of sneezes … immunoglobulin E (IgE) and histamine were suppressed in AR mouse serum, the levels of interleukin (IL)‐1&bgr;, IL‐4, and IL‐6 were reduced … mRNA and protein expression of cyclooxygenase 2 (COX‐2), IL‐1&bgr;, IL‐4, and IL‐6 were inhibited.”
Anti‐inflammatory effect of epigallocatechin gallate in a mouse model of ovalbumin‐induced allergic rhinitis“The supplementation of EGCG significantly inhibited MPO activity and histamine levels in the distal colon mucosa.”
(‐)‐epigallocatechin‐3‐gallate reduces experimental colon injury in rats by regulating macrophage and mast cell“ EGCG (1-30 microM) inhibited TNF-alpha and histamine induced endothelial TF expression and activity in a concentration dependent manner resulting in 87% reduction of TF expression (n=5; p<0.001); in contrast, expression of tissue factor pathway inhibitor was not affected (n=4; p=NS).”
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