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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Histamine
supplement:
Caffeic Acid
Research Papers that Mention the Interaction
“Overall, the current study demonstrated that caffeic acid has anti-itch effects by inhibition of multiple itch mechanisms induced by histamine , chloroquine and SLIGRL-NH2.”
Caffeic acid exhibits anti-pruritic effects by inhibition of multiple itch transmission pathways in mice.“In addition, phenylpropanoid glycosides (25mg/kg) significantly inhibited the recruitments of leukocytes, … and eosinophils into lung, Furthermore, 1-O-caffeoyl glycoside, acteoside and caffeic acid significantly (P<0.05) inhibited protein … a dose of 25mg/kg, and histamine content and PLA(2) activity at … of 50mg/kg, in BALF.”
Anti-asthmatic effects of phenylpropanoid glycosides from Clerodendron trichotomum leaves and Rumex gmelini herbes in conscious guinea-pigs challenged with aerosolized ovalbumin.“Both COX inhibitors (ibuprofen and indomethacin) and LOX inhibitors (baicalein and caffeic acid ) inhibited ATP-induced histamine in a dose dependent manner.”
“ Caffeic acid solubilized in Cremophor RH40 decreased histamine levels, too.”
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