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Last Updated: 3 years ago
Possible Interaction: Histamine and 1-(P-Hydroxybenzyl)-6,7-Dihydroxy-1,2,3,4-Tetrahydroisoquinoline
Research Papers that Mention the Interaction
“Additionally, HG reduced the levels of IgE, histamine , and IL-4 in the serum of AR mice, and regulated imbalance in Th1/Th2 cells.”
“In HNEpCs, HG inhibited the histamine-induced mRNA expression and secretion of interleukin (IL)-6, and IL-8, as well as the expression of MUC5AC and the phosphorylation of NF-κB. Moreover, HG affected the changes of AKT1, EGFR, c-Jun, iNOS, and JAK2 induced by histamine.”
Higenamine alleviates allergic rhinitis by activating AKT1 and suppressing the EGFR/JAK2/c-JUN signaling.
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