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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Hexobarbital
supplement:
NADH
Research Papers that Mention the Interaction
“ Hexobarbital increased in a dose dependent manner both NADPH, NADH , and NADPH/NADH dependent H2O2 production.”
Influence of age, hexobarbital, and aniline on NADPH/NADH dependent hydrogen peroxide production in rat hepatic microsomes.“The oxidation of added NADH is increased by hexobarbital , ethylmorphine and SKF 525-A. Lineweaver-Burk transformation of the NADH oxidation rates yields straight lines for xenobiotic substrates suggesting Michaelis constants similar to those obtained from metabolic experiments.”
“The addition of NADH to reaction mixtures containing a NADPH-generating system increased the maximum velocities of amobarbital, hexobarbital , and pentobarbital by 77, 249, and 47%, respectively.”
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