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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Hexachlorocyclohexane and Vitamin E

drug:

Hexachlorocyclohexane

supplement:

Vitamin E

Research Papers that Mention the Interaction

“Results suggest that vitamin E may exert a slightly protective role in cell defense against lipophilic pro-oxidant xenobiotics such as lindane.”
Lindane-induced cytotoxicity and the role of vitamin E in Chinese hamster ovary (CHO-K1) cells
Toxicology mechanisms and methods  •  2009  |  View Paper
“All these changes are suppressed by the administration of alpha-tocopherol (100 mg/kg) or the Kupffer cell inactivator gadolinium chloride (10 mg/kg) prior to gamma-hexachlorocyclohexane.”
Effects of acute gamma-hexachlorocyclohexane intoxication in relation to the redox regulation of nuclear factor-kappaB, cytokine gene expression, and liver injury in the rat.
Antioxidants & redox signaling  •  2004  |  View Paper
“The antioxidant vitamin E (100 microM) prevented inhibition of dye-coupling by PB and lindane and partially that by DDT.”
Inhibition of intercellular communication in rat hepatocytes by phenobarbital, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) and gamma-hexachlorocyclohexane (lindane): modification by antioxidants and inhibitors of cyclo-oxygenase.
Carcinogenesis  •  1993  |  View Paper