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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Hexachlorocyclohexane and Iron, Dietary

Research Papers that Mention the Interaction

Lindane and iron led to 504 and 210% increases in the content of hepatic protein carbonyls as an index of oxidative stress, with a 706% enhancement being produced by their combined administration.
Lindane increased NO generation by 106% without changes in generation of O2(.-), whereas iron enhanced both parameters by 109 and 80% over control values, respectively, with a net 33 and 46% decrease, respectively, being elicited by the combined treatment related to iron overload alone.
Toxicology letters  •  2001  |  View Paper
In contrast, the accumulation of Fe was increased in presence of HCH at higher concentrations.
The accumulation of HCH was decreased in presence of Fe at higher concentrations.
The results showed an increase in malondialdehyde content and potassium ion leakage with increase in HCH concentrations, however, the presence of Fe played a protective role.
Chemosphere  •  2002  |  View Paper