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Discover Supplement-Drug Interactions
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Last Updated: 5 months ago
supplement:
Hesperidin
drug:
Methotrexate
Research Papers that Mention the Interaction
“These findings suggest that Hsd may be able to prevent neurotoxic effects of MTX by reducing oxidative stress and enhancing hippocampal neurogenesis.”
Neuroprotective effects of hesperidin against methotrexate-induced changes in neurogenesis and oxidative stress in the adult rat.“Moreover, co-administration of HD with MTX remarkably upregulated the expression of Nrf2 and HO-1 compared with the MTX group.”
“RESULTS On the 4th day, crypt injury in the MTX plus HES group (1.00 ± 0.00) was less than that in the MTX group (2.00 ± 0.89; p < 0.05).”
“ RESULTS On the 4th day, crypt injury in the MTX plus HES group (1.00 ± 0.00) was less than that in the MTX group (2.00 ± 0.89; p < 0.05).”
The Protective Effect of Hesperidin on Methotrexate-Induced Intestinal Epithelial Damage in Rats: An Experimental Study
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