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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Hesperidin and Insulin

supplement:

Hesperidin

drug:

Insulin

Research Papers that Mention the Interaction

Results: Hesperidin (both concentrations) significantly reduced cells survival in the presence and absence of insulin compared to untreated cells in a time-dependent manner (P < 0.05).
Journal of cancer research and therapeutics  •  2018  |  View Paper
Conclusion: In combination with insulin, hesperidin not only attenuated the diabetic condition but also reversed neuropathic pain via control over hyperglycemia as well as hyperlipidemia to down-regulate generation of free radical, release of pro-inflammatory cytokines as well as elevation in membrane bound enzyme.
Pharmaceutical biology  •  2014  |  View Paper
Hesperidin prominently decreased serum amylase and lipase activities, and markedly increased insulin level, pancreatic antioxidant defense mechanism, whereas iNOS, NF-κB, IL-6 and TNF-α levels significantly decreased.
Life sciences  •  2020  |  View Paper
Based on the within-group analysis, hesperidin led to significant decrease in serum levels of glucose, insulin , triglyceride, total cholesterol, low density lipoprotein cholesterol, TNF-α and hs-CRP, while in control group only glucose and insulin significantly decreased.
European Journal of Nutrition  •  2019  |  View Paper