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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Hesperidin
drug:
Hydrogen Peroxide
Research Papers that Mention the Interaction
“Orange and lemon juices as well as hesperidin and limonene exhibit antigenotoxic activity against hydrogen peroxide used as an oxidative genotoxin.”
Role of Citrus Juices and Distinctive Components in the Modulation of Degenerative Processes: Genotoxicity, Antigenotoxicity, Cytotoxicity, and Longevity in Drosophila“ Hesperidin also reversed the activity of H2O2 on inhibiting the Col2a1, aggrecan, and SOX9 gene expression and increasing the gene expression of caspase 3, IL-1β, TNFα, iNOS, and MMP13.”
Effects of Hesperidin on H2O2-Treated Chondrocytes and Cartilage in a Rat Osteoarthritis Model“These observations clearly demonstrate that hesperidin provides strong cellular antioxidant protection against the damaging effects induced by paraquat and peroxide hydrogen.”
Antioxidant activity of the flavonoid hesperidin in chemical and biological systems.
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