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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Hesperidin
supplement:
Hesperetin
Research Papers that Mention the Interaction
“ HPD and HPT are not always consistent in some biological activities, even if they have the same skeletal structure.”
Metabolism study of hesperetin and hesperidin in rats by UHPLC-LTQ-Orbitrap MS n“Conclusion: The docking simulation revealed that HT and HD block the enzyme entrance channel and prevent the substrates from accessing the enzyme active sites.”
“In addition, the area under the curve values for total hesperetin after administration of Bg1A-treated hesperidin were approximately 4-fold higher by oral administration and 3-fold higher by intravenous administration, respectively.”
“This feature was reproduced and confirmed ex‐vivo after repetitive administration of hesperidin and hesperetin in‐vivo for one week (500 mg kg−1 orally) before in‐vitro testing against the challenging effects of 4‐AP and TEA.”
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