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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Hesperidin and Celiprolol

supplement:

Hesperidin

Research Papers that Mention the Interaction

Concomitant administration of orange juice or hesperidin with celiprolol significantly decreased the area under the plasma concentration-time curve (AUC) by 74% and 75%, respectively, compared with control.
These findings suggest that hesperidin is responsible for the decreased absorption of celiprolol and that orange juice taken with celiprolol has an inhibiting effect on intestinal absorption of the drug.
Biopharmaceutics & drug disposition  •  2008  |  View Paper