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Last Updated: 3 years ago

Possible Interaction: Heroin and Quinine

drug:

Heroin

supplement:

Quinine

Research Papers that Mention the Interaction

In the midst of the 1930s malaria outbreak, the population at risk started to cut heroin with quinine to prevent malaria infection (1).
Annals of Internal Medicine  •  2019  |  View Paper
An increase in the causal use of heroin in combination with ethanol and quinine is the probable cause of this epidemic.
Science  •  1984  |  View Paper
However, thrombocytopenia from consumption of quinine water ("cocktail purpura") has been described 2 and quinine used as an adulterant in heroin has been suspected of causing thrombocytopenia associated with heroin abuse.
Archives of internal medicine  •  1983  |  View Paper
To our knowledge, this report is the first to confirm that quinine used as an adulterant can induce immunologic thrombocytopenia following an injection of heroin.
Archives of internal medicine  •  1983  |  View Paper
An immunologic response to the quinine used to "cut" heroin caused oral manifestations of thrombocytopenic purpura.
Oral surgery, oral medicine, and oral pathology  •  1978  |  View Paper
Abstract A 40-year-old male heroin addict developed optic atrophy after taking large quantities of heroin diluted with quinine.
Annals of internal medicine  •  1971  |  View Paper
Quinine is added to heroin to increase its volume, yet maintain the bitter taste used as a "rule of thumb" for heroin identity by the user.
JAMA  •  1971  |  View Paper