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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Heroin and Glutathione

drug:

Heroin

supplement:

Glutathione

Research Papers that Mention the Interaction

BACKGROUND Animal studies suggest that exposure to either of the two widely used drugs of abuse, heroin or cocaine, causes depletion of the antioxidant, reduced glutathione , a hallmark of oxidative stress, in the brain.
Drug and alcohol dependence  •  2018  |  View Paper
Also, single-dose treatments of mice with heroin increased the total hepatic content of CYP, AHH, NADPH-cytochrome c reductase, and glutathione level by 126, 72, 39, 205%, respectively.
Toxicology  •  2003  |  View Paper