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Last Updated: 3 years ago

Possible Interaction: Heparin and Quinidine

drug:

Heparin

supplement:

Quinidine

Research Papers that Mention the Interaction

heparin … quinidine , there were significant increases in the mean (+/- SD) right ventricular effective refractory period (266 +/- 24 versus 279 +/- 23; p less than 0.025), free … +/- 0.1 microgram/ml; p less than 0.001) but no changes in heart rate, corrected QT interval, or total plasma quinidine concentration.
American heart journal  •  1989  |  View Paper
Anticoagulants, such as heparin , have been noted to reduce the extent of protein binding of quinidine.'
Drug intelligence & clinical pharmacy  •  1987  |  View Paper
Heparin inhibits the pancreatic TUA in presence or absence of quinidine.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1961  |  View Paper
In the experiments on rabbits it was shown that quinidine administered intravenously in a dose of 5 mg/kg exerts no effect on the blood coagulability but decreases the degree and duration of the anticoagulant effect of heparin.
Farmakologiia i toksikologiia  •  1989  |  View Paper