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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Heparin and Lysine

drug:

Heparin

supplement:

Lysine

Research Papers that Mention the Interaction

Inhibition by heparin of the oxidation of lysine in collagen by lysyl oxidase.
American journal of respiratory and critical care medicine  •  2017  |  View Paper
Modification of a limited number of lysine and arginine residues in full-length MPI led to a 6-fold decrease in affinity for heparin.
Biochemistry  •  1995  |  View Paper
Analysis of several enteroviruses of the same species as CAV9, Human enterovirus B (HEV-B), identified examples from 5 types in which blocking of infection by heparin was coincident with an arginine (or another basic amino acid, lysine ) at a position corresponding to 132 in VP1 in CAV9.
Journal of Virology  •  2012  |  View Paper
Mutation of residues Lys 321, Arg 405, Arg 407, Lys 409, and Lys 416 resulted in a decrease in affinity for heparin.
Journal of lipid research  •  1998  |  View Paper
Each helix has four lysines , which have been implicated in heparin binding.
Proteins  •  1992  |  View Paper