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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“The1H NMR resonance of the histidine of human platelet factor 4 exhibiting the lowerpKa value also is perturbed upon heparin binding to a greater degree than the histidine resonance exhibiting the higherpKa, thereby suggesting comparable heparin-protein interactions in bovine and human platelet factor 4.”
Comparative studies of the interaction of human and bovine platelet factor 4 with heparin using histidine NMR resonances as spectroscopic probes“The resonance of the H-2 atom of the histidine , considered to be the N-terminal residue and to be located in the heparin binding-site, is strongly perturbed by heparin binding both to native and modified antithrombin.”
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