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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Heparin
supplement:
Glutamic Acid
Research Papers that Mention the Interaction
“Replacement of this lysine with glutamic acid reduces the apparent affinity of HBGF-1 for immobilized heparin (elutes at 0.45 M NaCl vs. 1.1 M NaCl for wild-type).”
Possible dissociation of the heparin-binding and mitogenic activities of heparin-binding (acidic fibroblast) growth factor-1 from its receptor-binding activities by site-directed mutagenesis of a single lysine residue“Neutralization of basic amino acids in the PCI molecule by glutamic acid , which prevented in a dose-dependent way the inhibitory effect of heparin , did not have any effect on the tissue-kallikrein-PCI interaction.”
Heparin binding of protein-C inhibitor--analysis of the effect of heparin on the interaction of protein-C inhibitor with tissue kallikrein.
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