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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Heparin and Folate

drug:

Heparin

supplement:

Folate

Research Papers that Mention the Interaction

Folate conjugation unexpectedly allowed the self-assembly of heparin , where a majority of the folate molecules (>80%) resided inside the core of the nanoparticle.
Nanoscale  •  2015  |  View Paper
A hitherto unreported inhibitory effect of heparin on folate binding was noticed.
Acta haematologica  •  1977  |  View Paper
It was estimated that heparin bound several orders of magnitude less strongly than folate with an average dissociation constant in the 1–10 μM range.
Electrophoresis  •  2006  |  View Paper
Folate blocks the increases in the phosphatase activity and in the excretion of choline that are ordinarily produced by a mixture of glycine and heparin or by cortisol.
The Journal of biological chemistry  •  1972  |  View Paper