Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 5 years ago

Possible Interaction: Heparin and Folate

drug:

Heparin

supplement:

Folate

Research Papers that Mention the Interaction

“ Folate conjugation unexpectedly allowed the self-assembly of heparin , where a majority of the folate molecules (>80%) resided inside the core of the nanoparticle.”
Nanoscale  •  2015  |  View Paper
“A hitherto unreported inhibitory effect of heparin on folate binding was noticed.”
Acta haematologica  •  1977  |  View Paper
“It was estimated that heparin bound several orders of magnitude less strongly than folate with an average dissociation constant in the 1–10 μM range.”
Electrophoresis  •  2006  |  View Paper
“ Folate blocks the increases in the phosphatase activity and in the excretion of choline that are ordinarily produced by a mixture of glycine and heparin or by cortisol.”
The Journal of biological chemistry  •  1972  |  View Paper