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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Hemin and Calcium Supplement

drug:

Hemin

Research Papers that Mention the Interaction

Both hemin and exogenous CO significantly raised cGMP levels in basophils and blunted the rise of calcium levels caused by immunological activation.
European journal of pharmacology  •  2003  |  View Paper
In response to hemin limitation and in the presence of calcium there was a moderate increase in recA promoter activity.
Oral microbiology and immunology  •  2001  |  View Paper
Hemin abated PLC activity (29.6±1.5 nmol/min/mL versus 3.1±0.9 …/mL; n=5, P<0.01) and this was accompanied by depleted levels of intracellular calcium (551±46 nM versus 103.2±6.3 nM; …, P<0.01) in the aorta of SHR.
The International journal of angiology : official publication of the International College of Angiology, Inc  •  2007  |  View Paper
Attempts to characterize this quasi-lipoxygenase activity revealed that calcium potentiated the quasi-lipoxygenase activities of hemoproteins (hemoglobin, myoglobin, myeloperoxidase, catalase, cytochrome c) and hemin at the physiological pH of 7.5.
Free radical biology & medicine  •  1998  |  View Paper
Furthermore, hemin suppressed phospholipase C activity, attenuated inositol 1,4,5-triphosphate, and reduced resting intracellular calcium in the aorta.
Furthermore, hemin suppressed phospholipase C activity, attenuated inositol 1,4,5-triphosphate, and reduced resting intracellular calcium in the aorta.
Journal of hypertension  •  2008  |  View Paper