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Try: Ginkgo, Methotrexate, Glucosamine

Last Updated: 5 years ago

Possible Interaction: Hemin and Ascorbate

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drug:

Hemin

supplement:

Ascorbate

Research Papers that Mention the Interaction

“Certain transition metals and hydrogen donors, such as hydroquinone and ascorbate , which have been shown to stimulate the catalytic activity of ferriproroporphyrin IX in the decomposition of 15-hydroperoxy-prostaglandin E1 are inhibitors of thromboxane B2 formation.”

Biosynthesis of thromboxane B2: assay, isolation, and properties of the enzyme system in human platelets.

Prostaglandins • 1976 | View Paper

“ Hemin shields the enzyme from ascorbate plus DFO attack but not from ascorbate alone.”

Prooxidant action of desferrioxamine: enhancement of alkaline phosphatase inactivation by interaction with ascorbate system.

Archives of biochemistry and biophysics • 1990 | View Paper

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