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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Hemin and Ascorbate

drug:

Hemin

supplement:

Ascorbate

Research Papers that Mention the Interaction

Certain transition metals and hydrogen donors, such as hydroquinone and ascorbate , which have been shown to stimulate the catalytic activity of ferriproroporphyrin IX in the decomposition of 15-hydroperoxy-prostaglandin E1 are inhibitors of thromboxane B2 formation.
Prostaglandins  •  1976  |  View Paper
Hemin shields the enzyme from ascorbate plus DFO attack but not from ascorbate alone.
Archives of biochemistry and biophysics  •  1990  |  View Paper