“It is concluded that quinidine and halothane act synergistically to decrease action potential amplitude, lower RMP, and prolong conduction.”
“Severe depression of conduction often progressed to conduction block or inexcitability when halothane , 2%, was administered during superfusion with therapeutic concentrations of quinidine.”
“Synergistic interactions between halothane and quinidine were found on RMP, APamp, APD100, and CT.”