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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Haloperidol
supplement:
Tryptophan
Research Papers that Mention the Interaction
“Liver demonstrated a significant increase (p < 0.05) in the concentration of tryptophan, however, a slight increase was found in the concentration of brain tryptophan following haloperidol treatment.”
Alterations in the level of neurotransmitters associated with the chronic treatment of antipsychotic drugs.“Clozapine, but not chlorpromazine, haloperidol , thioridazine, or loxapine, increases the concentrations of tryptophan , serotonin, and 5-hydroxyindoleacetic acid in the brain of the rat.”
“Finally, the combination of haloperidol plus tryptophan was found to cause a long-lasting increase in spontaneous chewing movements that lasted 56 days after the first injection.”
“Clozapine, but not chlorpromazine, haloperidol , thioridazine, or loxapine, increases the concentrations of tryptophan , serotonin, and 5-hydroxyindoleacetic acid in the brain of the rat.”
“Administration of tryptophan followed by haloperidol injection increased tryptophan and 5HT concentrations and decreased DA levels.”
Effect of co administration of haloperidol and large neutral amino acids (tryptophan and valine) on rats striatal dopamine, serotonin and their metabolism.
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