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Last Updated: 3 years ago

Possible Interaction: Haloperidol and Quinidine

supplement:

Quinidine

Research Papers that Mention the Interaction

On the other hand, the coadministration of carbamazepine, phenytoin, phenobarbital, rifampicin or quinidine affects the pharmacokinetics of haloperidol to an extent that alterations in clinical consequences would be expected.
Pharmacokinetic interactions occur between haloperidol and various drugs given concomitantly, for example, carbamazepine, phenytoin, phenobarbital, fluoxetine, fluvoxamine, nefazodone, venlafaxine, buspirone, alprazolam, rifampicin (rifampin), quinidine and carteolol.
Clinical pharmacokinetics  •  1999  |  View Paper
Quinidine , the most specific inhibitor for this cytochrome P450 potently inhibited the oxidative conversion of reduced haloperidol to haloperidol.
British journal of clinical pharmacology  •  1991  |  View Paper