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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Haloperidol
supplement:
Progesterone
Research Papers that Mention the Interaction
“The antagonistic effects of haloperidol and progesterone on the potentiating effects of (+)pentazocine and pregnenolone suggested that these ligands might act through a common mechanism.”
Modulation of bradykinin‐induced calcium changes in SH‐SY5Y cells by neurosteroids and sigma receptor ligands via a shared mechanism“Coadministration of progesterone also reversed the decrease in dopamine levels induced by chronic haloperidol treatment, an effect which was again reversed by pre treatment with finasteride.”
Progesterone attenuates neuroleptic-induced orofacial dyskinesia via the activity of its metabolite, allopregnanolone, a positive GABAA modulating neurosteroid“ Progesterone (100 nM) mimicked the antagonistic effect of haloperidol and 1-[2-(3,4-dichlorophenyl)ethyl]-4-methyl-piperazine.”
“ Haloperidol effects were higher in both 17 beta-estradiol and 17 beta-estradiol plus progesterone treated rats.”
“ Progesterone induced ovulation was blocked by prior treatment with haloperidol.”
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