Possible Interaction: Haloperidol and Niacin

“On the other hand, the choice accuracy deficit induced by nicotinic blockade with mecamylamine is potentiated by haloperidol.”

“ Haloperidol … nicotinic secretory response during S2; so, while the ratio S2/S1 was 0.5 in control conditions, this ratio increased significantly to 0.95 if … present during S2, suggesting that the presence of this dopaminergic antagonist removed a negative feed‐back mechanism that inhibits nicotine‐evoked catecholamine release.”