Possible Interaction: Haloperidol and Lithium Carbonate

“ Lithium carbonate plus haloperidol was favored both for affective schizo-affectives and for schizophrenic schizo-affectives.”

“Modest but statistically significant differences in favor of lithium carbonate plus haloperidol were found by week 5, using the Brief Psychiatric Rating Scale.”

“It is suggested that lithium carbonate and haloperidol together should be seriously considered in the treatment of HC when patients are excessively irritable and impulsive.”

“A 44-year-old maniacodepressive woman developed acute encephalopathy due to the association of lithium carbonate and haloperidol.”

“A 27 year old male with a history of schizo-affective disorder became progressively obtunded and developed generalised seizures and rigidity a few days after receiving haloperidol , diazepam and lithium carbonate for acute exacerbation of his psychosis.”

“A 27 year old male with a history of schizo-affective disorder became progressively obtunded and developed generalised seizures and rigidity a few days after receiving haloperidol , diazepam and lithium carbonate for acute exacerbation of his psychosis.”

“Toxic irreversible encephalopathic syndromes developed in 2 patients treated with lithium carbonate and haloperidol.”

“Reported is a 19-year-old manic-depressive patient who developed persistent dysarthria with coexisting apraxia while on a combination of high dose haloperidol and lithium carbonate.”

“A combination of lithium carbonate and haloperidol caused a greater increase in lipid peroxidation than did either lithium carbonate or haloperidol alone.”

“ Lithium carbonate , given concurrently with the haloperidol , partially prevented the development of ICSS supersensitivity.”