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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Preincubation of the myocytes with 5 mM ribose for times up to 1 hour modestly increased salvage rates of guanosine in aerobic cells.”
Anoxia inhibits guanosine salvage in cardiac myocytes“At lower guanosine levels in the presence of ribose , cell guanine concentrations limit the rate of guanosine incorporation into 5′-nucleotides.”
“The data presented show significant incorporation of guanosine into the 5′-nucleotide pool, and a marked stimulation of that incorporation by ribose.”
“ Ribose 1-phosphate, another product of the reaction, gave noncompetitive inhibition with guanosine as variable substrate, and an inhibition constant of 3.61 x 10(-4) M was calculated.”
“Under these conditions ribose also reacts with the primary amine group of adenosine, guanosine and probably guanine to form the corresponding ribosylaminopurines, while hypoxanthine fails to react.”
Studies in prebiotic synthesis. VI. Synthesis of purine nucleosides.
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