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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Guanidines
supplement:
Tubocurarine
Research Papers that Mention the Interaction
“ Guanidine reversed the blocking effect of d-tubocurarine , the maximal effect occurring with 3 mM at 15 min.”
“The present results show that guanidine reverses the blockade induced by dibekacin and d-tubocurarine , being more potent against the former drug.”
Influence of extracellular calcium on the actions of guanidine at the rat neuromuscular junction.“ Guanidine or tetraethylammonium (TEA) increased m and n, but … effect on p. At junctions depressed by d-tubocurarine , both compounds enhanced the amplitude of the initial end-plate potential, caused an accelerated rate of … end-plate potential amplitudes and raised the steady-state level of end-plate potential amplitude.”
“Among the compounds tested, and in decreasing order of potency, were NN-dimethylguanidine, N-methylguanidine, guanidine and N-aminoguanidine which antagonized or prevented tubocurarine or gallamine triethiodide-induced paralysis.”
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