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Possible Interaction: Guanidines and Tubocurarine

supplement:

Guanidines

supplement:

Tubocurarine

Research Papers that Mention the Interaction

Guanidine reversed the blocking effect of d-tubocurarine , the maximal effect occurring with 3 mM at 15 min.
The present results show that guanidine reverses the blockade induced by dibekacin and d-tubocurarine , being more potent against the former drug.
Archives internationales de pharmacodynamie et de therapie  •  1992  |  View Paper
Guanidine or tetraethylammonium (TEA) increased m and n, but … effect on p. At junctions depressed by d-tubocurarine , both compounds enhanced the amplitude of the initial end-plate potential, caused an accelerated rate of … end-plate potential amplitudes and raised the steady-state level of end-plate potential amplitude.
The Journal of pharmacology and experimental therapeutics  •  1976  |  View Paper
Among the compounds tested, and in decreasing order of potency, were NN-dimethylguanidine, N-methylguanidine, guanidine and N-aminoguanidine which antagonized or prevented tubocurarine or gallamine triethiodide-induced paralysis.
British journal of pharmacology and chemotherapy  •  1962  |  View Paper