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Last Updated: 3 years ago

Possible Interaction: Guanidines and Trypsin

supplement:

Guanidines

supplement:

Trypsin

Research Papers that Mention the Interaction

“In vitro digestibility of guanidinated casein by trypsin and chymo-trypsin was much lower than that of intact casein.”
A Protein Less Sensitive to Trypsin, Guanidinated Casein, Is a Potent Stimulator of Exocrine Pancreas in Rats
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1995  |  View Paper
“Microbial trypsin has about a 3-fold greater affinity for guanidine and about a 20-fold lower Km for Nα-benzoyl-l-arginine-p-nitroanilide than does bovine trypsin.”
“Therefore, guanidine appears to stabilize microbial trypsin.”
The proteolytic enzymes of the K-1 strain of Steptomyces griseus obtained from a commerical preparation (pronase). Stabilization of the trypsin component by calcium and guanidine.
The Journal of biological chemistry  •  1974  |  View Paper