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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Guanidines
supplement:
Threonine
Research Papers that Mention the Interaction
“In insulin, HisB5 → Thr markedly destabilizes the hormone ( ΔΔGu 2.0 ± 0.2 kcal/mol), impairs chain combination, and blocks cellular secretion of proinsulin.”
Contribution of Residue B5 to the Folding and Function of Insulin and IGF-I“Surprisingly, the introduction of a guanidine moiety always led to a decrease in THR inhibiting properties.”
Investigation of mechanism-based thrombin inhibitors: Implications of a highly conserved water molecule for the binding of coumarins within the S pocket.
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