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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Guanidines
drug:
Tetraethylammonium
Research Papers that Mention the Interaction
“The antiguanidine agents choline, dimethylethanolamine and tetraethylammonium , but not methionine, inhibited guanidine uptake by HeLa cells.”
Guanidine uptake by HeLa cells and its inhibition by some antiguanidine agents.“ Guanidine uptake was only minimally inhibited by organic cations such as tetraethylammonium , N1-methylnicotinamide, and choline, but many other organic cations such as amiloride, clonidine, imipramine, and harmaline caused considerable inhibition.”
Multiple transport systems for organic cations in renal brush-border membrane vesicles.“The efficiency of 4-aminopyridine and animal toxins is explained by an action on the nerve ending, by increasing Ca2+ from an interval compartment of the cell, whereas antagonism produced by guanidine and tetraethylammonium involves uptake of Ca2+ from the external medium.”
“A similar parallel shift occurs in the presence of tetraethylammonium and guanidine.”
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